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We investigate finite-time blow-up for nonnegative solutions to the Cauchy problem associated with semilinear parabolic equations driven by a mixed local–nonlocal operator. The reaction term is assumed to satisfy suitable structural hypotheses, the prototype being with . By adapting the Kaplan method to the present framework, we prove that solutions blow up in finite time whenever the initial datum is sufficiently large. In the prototype case , this conclusion holds for every . As a particular case of our operator, we also include the fractional Laplacian; to the best of our knowledge, this type of result is new even in that special case.

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