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We study the fast reaction limit for a two-component reaction-diffusion system with asymmetric reaction terms, where only one component diffuses. For nonnegative and mutually segregated initial data, we prove that the initial interface vanishes instantaneously. More precisely, the diffusive component converges uniformly to the solution of the heat equation, while the non-diffusive component vanishes away from the initial time. The proof is based on explicit barriers and a comparison argument, and applies under both Dirichlet and Neumann boundary conditions.

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