We extend the model with neutral leptons (331LHN) by introducing scalar leptoquarks. We determine the particle content of the leptoquark multiplets and their Yukawa interactions with fermions. We find that a singlet leptoquark can fully account for the discrepancy in the muon anomalous magnetic moment . The corresponding leptoquark mass is constrained to be ~TeV, consistent with current LHC bounds. We further consider the updated based on recent lattice QCD results, which strengthen the lower bound to ~TeV. Combining with low-energy leptonic observables, including charged lepton flavor violation and the – conversion rate, we constrain the viable parameter space. The allowed leptoquark Yukawa couplings exhibit a normal hierarchical pattern under all constraints. We also investigate the collider phenomenology of the singlet leptoquark, showing that its QCD-driven pair production leads to suppressed signal rates at the LHC for multi-TeV masses, while future hadron colliders can significantly extend the discovery reach.

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