Benchmarking Current-to-Voltage Amplifiers for Quantum Transport Measurements

Accurate electrical amplification is essential in molecular electronics for measuring conductance through atomic and molecular junctions, where currents often span several orders of magnitude. In this work, we present a systematic design and comparative analysis of four current-to-voltage ($I\text{–}V$) amplifier architectures: single-stage linear, series-linear, logarithmic, and multi-stage cascaded, specifically optimized for break junction (BJ) techniques, including scanning tunneling microscopy (STM-BJ) and mechanically controllable break junctions (MCBJ). Each configuration is evaluated based on sensitivity, noise performance, and dynamic range. Our results characterize the trade-offs between circuit complexity and noise, providing a robust framework and practical guidelines for selecting amplification schemes in quantum transport experiments.