In this paper, we study generating functions of Erdélyi’s multivariate Laguerre polynomials with a varying complex parameter. Our main result is a multiple generating function from which several useful consequences can be derived. We also present an interesting evaluation for a generating function of the main diagonal sequence which involves in a natural way the well-known Le Roy function ([Darboux Bull. 24 (2) (1899), 245–268]; [Toulouse Ann. 2 (2) (1900), 317–430]). The significance of the multivariate Laguerre polynomials is demonstrated by observing that this class not only includes the generalized Hardy-Hille formula and the product formula but also contains the multiple Laguerre polynomials of the second kind as its important special cases. The paper gives in detail various consequences of the results presented in this paper and also mentions possible lines for future work.

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