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We present the first results on the nuclear modification factor in OO collisions at LHC energies by the ALICE experiment. The measurement of the modification of hadron production in nuclear collisions compared to a vacuum baseline in pp collisions is a valuable probe for parton energy loss in the hot medium. The ALICE results show significant (up to 4) suppression of production in OO collisions compared to the pp reference, and up to 2.4 deviation w.r.t. model predictions that include only cold nuclear matter effects.

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