By comparing simultaneous multigraded blow-ups with suitable iterated blow-up construction, we establish a birational correspondence between the associated exceptional divisors. We further investigate blow-ups arising from rational maps to multiprojective spaces and derive intersection-theoretic formulas for the Chern classes of the resulting exceptional divisors and pullback of tautological line bundles. These constructions have two main applications. First, they yield a proof of the product formula for Segre classes without any pure-dimensionality hypothesis. Second, they lead to a degree formula for arbitrary closed subschemes of multiprojective spaces, recovering and extending the classical formula of van der Waerden.

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