Ultrafast chiral sensing with an ultraviolet vector beam

We present a robust, ultrafast and highly efficient setup for distinguishing molecular enantiomers by combining ultrafast techniques with vector beams, a type of topological light with azimuthally varying polarization. An infrared vector beam generates high-order harmonics in a sample of randomly oriented chiral molecules, resulting in the emission of an ultraviolet vector beam whose intensity profile carries information about the handedness of the chiral molecules. Our approach allows for spatial discrimination of molecular enantiomers, opening a new route for studying ultrafast chirality.