We prove the well-posedness and regularity of solutions in mixed-norm weighted Sobolev spaces for a class of second-order parabolic and elliptic systems in divergence form in the half-space subject to the conormal boundary condition. Our work extends results previously available for scalar equations to the case of systems of equations. The leading coefficients are the product of and bounded non-degenerate matrices, where . The leading coefficients are assumed to be merely measurable in the variable, and to have small mean oscillations in small cylinders with respect to the other variables. If the parameter , the lower-order coefficients are allowed to blow-up near the boundary. Our results readily generalize to infinite-dimensional equations in general real and complex Hilbert spaces.

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