We present helicity amplitudes at three loops in the heavy-top quark effective theory of QCD for the scattering of a Higgs boson and three light partons with full-color dependence. To obtain these results, we use integration-by-parts identities implemented in the code Blade and evaluate the master integrals using canonical differential equations. We obtain compact analytic expressions in terms of generalized polylogarithms suitable for numerical evaluation. We observe that sub-leading color contributions at three loops are numerically as significant as leading-color terms. Our amplitudes are key ingredients for precision LHC phenomenology, for example in production cross sections involving a Higgs boson and a hadronic jet.

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