We develop a local-to-global method for comparing a positive Radon measure potential with a reciprocal-scale multiplier on an unbounded complete metric measure space supporting a doubling measure and a weak -Poincaré inequality. The central local object is the genuinely mixed oscillation integral which cannot be controlled by the ordinary Poincaré inequality when is singular. We first prove a fixed-outer-domain content–capacity estimate at every positive codimensional gain. A ball-growth condition for then yields capacitary domination and a Maz’ya-type trace inequality, hence the desired mixed Poincaré estimate on normalized balls. A bounded-overlap normalized cover globalizes the local result and gives two-sided Fefferman–Phong inequalities and equivalence of the corresponding energy completions. The abstract theory is verified for Euclidean weights with generalized Schrödinger measure potentials, for reverse-Hölder function potentials, on Carnot groups, and for lower-dimensional singular measures. We also show that the natural structural assumption is the quadratic PI property: is not necessary, whereas a bare assumption with is insufficient. The Euclidean application yields form-domain equivalence, smooth form cores, self-adjoint realization, resolvent energy estimates, and local critical-multiplier bounds. Finally, the method supplies the mixed-measure step missing from a previously published generalized Schrödinger argument and gives a fixed-dilate finite-scale extension, for the naturally augmented measure, of the generalized Poincaré mechanism used in a later theory.

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