We investigate fractional heat semigroups generated by a class of anharmonic oscillators on of the form where and are real-valued polynomials with anisotropic growth. Using the Weyl–Hörmander calculus associated with the natural metric determined by , we show that the fractional powers , , are pseudo-differential operators with symbols in adapted classes . We prove fixed-time decay estimates for the fractional anharmonic heat semigroup on both Lebesgue and modulation spaces. In the Lebesgue setting, we establish sharp – estimates for the full range . For large time, the decay is exponential and governed by the smallest eigenvalue of , namely through the factor , while for small time the estimates reveal two distinct phase-space scales associated with the coercive growth of and , leading to anisotropic – smoothing. As applications, we study nonlinear fractional heat equations associated with . We prove local well-posedness in the supercritical Lebesgue range derive a lower blow-up rate for finite-time blow-up solutions, and obtain critical small-data global existence. We further prove global well-posedness and exponential decay for small initial data in modulation spaces. These results extend the heat semigroup theory for harmonic and model anharmonic oscillators to a broad class of anisotropic polynomial Hamiltonians.

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