This paper establishes a central limit theorem (CLT) for functionals of -bounded persistence diagrams arising from germ-grain random set models. Building on stabilisation methods for marked point processes, we show that, under certain conditions, these topological summaries exhibit asymptotic normality as the observation window increases, particularly for models with exponential decay of correlations. These results are applied in goodness-of-fit tests designed to detect spatial interactions such as clustering or repulsion. Using test statistics derived from rectangular partitions of persistence diagrams and functional summaries (e.g., the APF or the support function of the lift zonoid), the study distinguishes between different models. Finally, the methodology is applied to histological images of breast tissue.

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