Recent tunneling measurements on infinite-layer nickelates have revealed spatially varying superconducting symmetries, whose microscopic origin remains unclear. Motivated by this observation, we investigate the interplay between electron correlations and electron-phonon interactions in infinite-layer nickelates by combining first-principles calculations with the fluctuation-exchange-Migdal-Eliashberg theory. Our calculations show that spin fluctuations yield robust -wave superconductivity on the Ni orbital, whereas electron-phonon coupling induces -wave pairing on an interstitial orbital, leading to an superconducting state. The emergence of the -wave component is strongly carrier-density dependent: an intermediate electron-phonon coupling of stabilizes the state at but not at . These results imply that local oxygen defects tune the local electron density and form finite-size domains with distinct pairing symmetries, offering a compelling explanation for the spatially inhomogeneous superconducting symmetries observed in experiments.

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