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In this paper, we investigate direct and inverse problems for the time-fractional heat equation with a time-dependent leading coefficient for positive operators. First, we consider the direct problem, and the unique existence of the generalized solution is established. We also deduce some regularity results. Here, our proofs are based on the eigenfunction expansion method. Second, we study the inverse problem of determining the leading coefficient, and the well-posedness of this inverse problem is proved.

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