Motivated by understanding the scattering of gravitons and their superpartners from extended -strings in type IIB string theory via AdS/CFT, we study an integrated two-point function of stress tensor multiplet operators in the presence of a half-BPS line defect in super-Yang-Mills theory. We determine this integrated correlator at the five lowest non-trivial orders in at fixed Yang-Mills coupling and angle. Our calculations are performed explicitly when the line defect is a Wilson line, in which case we find a finite number of perturbative contributions at each order in , as well as instanton contributions. Using transformations, our results can also be applied to Wilson-'t Hooft line defects dual to extended -strings in the bulk. We analyze features of these integrated correlators in the weak coupling expansion by comparing with open-closed amplitudes of type IIB string theory on , as well as in its flat space limit. We predict new higher-derivative interaction vertices on the D1-brane and, more generally, on -strings.

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