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In this paper, we study weighted fractional Sobolev-Poincaré inequalities for irregular domains. The weights considered here are distances to the boundary to certain powers, and the domains are the so-called -John domains and -Hölder domains. Our main results extend that of Hajlasz-Koskela [J. Lond. Math. Soc. 1998] from the classical weighted Sobolev-Poincaré inequality to its fractional counter-part and Guo [Chin. Ann. Math. 2017] from the frational Sobolev-Poincaré inequality to its weighted case.

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