We present a Bayesian analysis of renormalization-group invariant nucleon-nucleon interactions at leading order in chiral effective field theory (EFT) with momentum cutoffs in the range 400–4000 MeV. We use history matching to identify relevant regions in the parameter space of low-energy constants (LECs) and subsequently infer the posterior probability density of their values using Markov chain Monte Carlo. All posteriors are conditioned on experimental data for neutron-proton scattering observables and we estimate the EFT truncation error in an uncorrelated limit. We do not detect any significant cutoff dependence in the posterior predictive distributions for two-nucleon observables. For all cutoff values we find a multimodal LEC posterior with an insignificant mode harboring a bound state. The and phase shifts emerging from the Bayesian analysis are less constrained and typically more repulsive compared to the results of a phase shift optimization. We expect that our inference will impact predictions for nuclei. This work demonstrates how to perform inference in the presence of limit-cycle-like behavior and spurious bound states, and lays the foundation for a Bayesian analysis of renormalization-group invariant EFT interactions beyond leading order.

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