In this paper, we investigate a chemotaxis-fluid system involving both the effect of potential force on cells and the effect of chemotactic force on fluid: \begin{equation*} \left{ \begin{split} \partial_t n + \cdot\nabla n & = Δn - \nabla\cdot\left(χ©n\nabla c\right) + \nabla\cdot(n\nablaφ), \ \partial_t c + \cdot\nabla c &= Δc - nf©, \ \partial_t + κ(\cdot\nabla) + \nabla P & = Δ - n\nablaφ+ χ©n\nabla c, \ \nabla\cdot &= 0 \end{split} \right. \end{equation*} in . One of the novelties and difficulties here is that the coupling in this model is stronger and more nonlinear than the most-studied chemotaxis-fluid model. We will first establish several extensibility criteria of classical solutions, which ensure us to extend the local solutions to global ones in the three dimensional chemotaxis-Stokes case and in the two dimensional chemotaxis-Navier-Stokes version under suitable smallness assumption on with the help of a new entropy functional inequality. Some further decay estimates are also obtained under some suitable growth restriction on the potential at infinity. As a byproduct of the entropy functional inequality, we also establish the global-in-time existence of weak solutions to the three dimensional chemotaxis-Navier-Stokes system. To the best of our knowledge, this seems to be the first work addressing the global well-posedness and decay property of solutions to the Cauchy problem of self-consistent chemotaxis-fluid system.

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