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Partial cubes are graphs that can be isometrically embedded into hypercubes. Convex cycles play an important role in the study of partial cubes. In this paper, we prove that a regular partial cube is a hypercube (resp., a Doubled Odd graph, an even cycle of length where ) if and only if all its convex cycles are 4-cycles (resp., 6-cycles, -cycles). In particular, the partial cubes whose all convex cycles are 4-cycles are equivalent to almost-median graphs. Therefore, we conclude that regular almost-median graphs are exactly hypercubes, which generalizes the result by Mulder [J. Graph Theory, 4 (1980) 107–110] – regular median graphs are hypercubes.

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