Special alternating knots with sufficiently many twist regions have no chirally cosmetic surgeries

We show that a special alternating knot with sufficiently large number (more than $63$) of twist regions has no chirally cosmetic surgeries, a pair of Dehn surgeries producing orientation-reversingly homeomorphic $3$-manifolds. In the course of proof, we provide the optimal upper bounds of the primitive finite type invariants of degree 2 and 3 that solve Willerton’s conjecture.