Temperature-dependent magnetic particle imaging with multi-harmonic lock-in detection

Advances in instrumentation and tracer materials are still required to enable sensitive and accurate 3D temperature monitoring by magnetic particle imaging. We have developed a magnetic particle imaging instrument to observe temperature variations using MPI, and discuss resolution dependence on temperature and harmonic number. Furthermore, we present a low noise approach using lock-in detection for temperature measurement, and discuss implications for a new detection modality of MPI.