Failure of Lefschetz hyperplane theorem

In this article, we give a counterexample to the Lefschetz hyperplane theorem for non-singular quasi-projective varieties. A classical result of Hamm-Lê shows that Lefschetz hyperplane theorem can hold for hyperplanes in general position. We observe that the condition of ``hyperplane’’ is strict in the sense that it is not possible to replace it by higher degree hypersurfaces. The counterexample is very simple: projective space minus finitely many points. Moreover, as an intermediate step we prove that the Grothendieck-Lefschetz theorem also fails in the quasi-projective case.