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In this paper, we consider the following Schrödinger-Poisson system with -laplacian \begin{equation} \begin{cases} -Δ_{p}u+V(x)|u|^{p-2}u+φ|u|^{p-2}u=f(u)\qquad&x\in^{3},\newline -Δφ=|u|^{p}&x\in^{3}. \end{cases}\notag \end{equation} We investigate the existence of multiple sign-changing solutions. By using the method of invariant sets of descending flow, we prove that this system has infinitely many sign-changing solutions. This system is new one coupled by Schrödinger equation of -laplacian with a Poisson equation. Our results complement the study made by Zhaoli Liu, Zhiqiang Wang, Jianjun Zhang (Annali di Matematica Pura ed Applicata, 195(3):775-794(2016)).

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