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The paper considers the asymptotic of the ratio of the number of primes not exceeding the primorial and the number of residues in the reduced system of residues for the given primorial. We study the relationship between asymptotic lower bounds for the values of the Jacobstal function and the maximum distance between successive primes. One algorithm for computing the Jacobstal function is given. The substantiation of the conjectures about the upper estimate of the maximum distance between successive prime numbers is given.

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