We study the following Lane-Emden system with a bounded regular domain of , , and exponents belonging to the so-called critical hyperbola . We show that, under suitable conditions on , least-energy (sign-changing) solutions exist, and they are classical. In the proof we exploit a dual variational formulation which allows to deal with the strong indefinite character of the problem. We establish a compactness condition which is based on a new Cherrier type inequality. We then prove such condition by using as test functions the solutions to the system in the whole space and performing delicate asymptotic estimates. If , , the system above reduces to a biharmonic equation, for which we also prove existence of least-energy solutions. Finally, we prove some partial symmetry and symmetry-breaking results in the case is a ball or an annulus.

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