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To avoid multicollinearity in regression analysis, Ye and Zhou(2013) proposed optimality criterion. By far the most popular models for modeling the response of a mixture experiment are the Scheffé models. However, there have been no reports about constructing optimal designs for mixture models. The paper constructs optimal designs for first-order and second-order Scheffé models. The analytical solutions for first-order and second-order Scheffé models are obtained. A series of numerical results and examples are given to illustrate the theory.

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