Based on maximally entangled states, we explore the constructions of mutually unbiased bases in bipartite quantum systems. We present a new way to construct mutually unbiased bases by difference matrices in the theory of combinatorial designs. In particular, we establish mutually unbiased bases with maximally entangled bases and one product basis in for arbitrary prime power . In addition, we construct maximally entangled bases for dimension of composite numbers of non-prime power, such as five maximally entangled bases in and , which improve the known lower bounds for , with in . Furthermore, we construct mutually unbiased bases with maximally entangled bases and one product basis in for arbitrary prime number .

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