We develop a comprehensive model for heavy-quark evolution in a realistic QGP, from their production in the initial collision to hadronic freeze-out. Heavy-quark transport is described by a Langevin approach including medium-induced radiation, coupled to a 2+1D viscous hydrodynamic bulk evolution. Transport coefficients are obtained from non-perturbative -matrix calculations with resonant correlations near the transition temperature. Hadronization is implemented via two fragmentation+recombination schemes: an improved sudden coalescence model and a resonance recombination model. We present results for key open heavy-flavor observables, i.e., the nuclear modification factor and elliptic flow, and compare to LHC Pb-Pb data at =5.02,TeV.}

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