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In the present work, we systematically study the proton radioactivity half-lives of 33 spherical nuclei based on the relationship between the Skyrme parameters and the macroscopic quantities of nuclear matter. Using the two-potential approach with the spherical Skyrme-Hartree-Fock model, the correlation between proton radioactivity half-life and macroscopic quantities was analyzed. Moreover, we obtained a new Skyrme parameter set by fitting the two most weighted macroscopic quantities. Compared with Skyrme parameters MSL0 and the theoretical model of proton radioactivity UDLP, the theoretical proton radioactivity half-life calculated by the new Skyrme parameter set can better reproduce the experimental data.

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