In this work we characterise the Hörmander classes on the open manifold . We show that by endowing the open manifold with a group structure, the corresponding global Fourier analysis on the group allows one to define a global notion of symbol on the phase space . Then, the class of pseudo-differential operators associated to the global Hörmander classes recovers the Hörmander classes defined by local coordinate systems. The analytic and qualitative properties of the classes are presented in terms of the corresponding global symbols. In particular, -Fefferman type estimates and Calderón-Vaillancourt theorems are analysed, as well as the spectral properties of the operators.

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