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In this paper we explore interactions between neutrinos and Dark Matter. In particular, we study how the propagation of astrophysical neutrinos can be modified by computing the most general potential generated by the galactic DM background. We use on-shell techniques to compute this potential in a completely model independent way and obtain an expression valid for any Dark Matter mass and spin. Afterwards, we use this expression to analyse under what circumstances such potential can be important at the phenomenological level, and we find that under some assumptions only ultra light scalar Dark Matter could be of any relevance to oscillation experiments.

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