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We present a demonstration of the design sampling and closure for the first comprehensive Bayesian model-to-data comparison of heavy-ion measurements with IP-Glasma initial conditions, in which we combine with state-of-the-art hydrodynamics (MUSIC), particlization (iS3D), and transport (SMASH). We further introduce a systematically-improvable method of sampling design points with better projection properties to explore the parameter space of the model for the first time in heavy-ion collisions.

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