In this paper we study some determinants and permanents. In particular, we investigate the new type determinants det[(i2+cij+dj2)p−2]1≤i,j≤p−1anddet[(i2+cij+dj2)p−2]0≤i,j≤p−1 modulo an odd prime p, where c and d are integers. We also pose some conjectures for further research.