In this paper we are interested in the following critical Hartree equation \begin{equation*} \begin{cases} -Δu =\displaystyle{\Big(\int_Ω\frac{u^{2_μ^\ast} (ξ)}{|x-ξ|^μ}dξ\Big)u^{2_μ^\ast-1}}+\varepsilon u ,~~Ω,\ u=0,~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~\partialΩ, \end{cases} \end{equation*} where , , is a small parameter, is a bounded domain in , and is the critical exponent in the sense of the Hardy-Littlewood-Sobolev inequality. By establishing various versions of local Pohozaev identities and applying blow-up analysis, we first investigate the location of the blow-up points for single bubbling solutions to above the Hartree equation. Next we prove the local uniqueness of the blow-up solutions that concentrates at the non-degenerate critical point of the Robin function for small.

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