In this paper, we study -higher index theory and its pairing with cyclic cohomology for both closed manifolds and compact manifolds with boundary. We first give a sufficient geometric condition for the vanishing of the -higher indices of Dirac-type operators on closed manifolds. This leads us to define an -version of higher rho invariants. We prove a product formula for these -higher rho invariants. A main novelty of our product formula is that it works in the general Banach algebra setting, in particular, the -setting. On compact spin manifolds with boundary, we also give a sufficient geometric condition for Dirac operators to have well-defined -higher indices. More precisely, we show that, on a compact spin manifold with boundary equipped with a Riemannian metric which has product structure near the boundary, if the scalar curvature on the boundary is sufficiently large, then the -higher index of its Dirac operator is well-defined and lies in the -theory of the -algebra of the fundamental group. As an immediate corollary, we see that if the Bost conjecture holds for the fundamental group of , then the -algebraic higher index of lies in the image of the Baum-Connes assembly map. By pairing the above -theoretic -index results with cyclic cocycles, we prove an -version of the higher Atiyah-Patodi-Singer index theorem for manifolds with boundary. A key ingredient of its proof is the product formula for -higher rho invariants mentioned above.

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