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In this paper, we study the Cauchy problem for the inhomogeneous biharmonic nonlinear Schrödinger (IBNLS) equation where , , , and . Under some regularity assumption for the nonlinear term, we prove that the IBNLS equation is locally well-posed in if , , and . Here if , and if . Our local well-posedness result improves the ones of Guzmán-Pastor [Nonlinear Anal. Real World Appl. 56 (2020) 103174] and Liu-Zhang [J. Differential Equations 296 (2021) 335-368] by extending the validity of and .

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