We study the existence of continuous (linear) operators from the Banach spaces of Lipschitz functions on infinite metric spaces vanishing at a distinguished point and from their predual spaces onto certain Banach spaces, including -spaces and the spaces and . For pairs of spaces and we prove that if they are endowed with topologies weaker than the norm topology, then usually no continuous (linear or not) surjection exists between those spaces. It is also showed that if a metric space contains a bilipschitz copy of the unit sphere of the space , then admits a continuous operator onto and hence onto . Using this, we provide several conditions for a space implying that is not a Grothendieck space. Finally, we obtain a new characterization of the Schur property for Lipschitz-free spaces: a space has the Schur property if and only if for every complete discrete metric space with cardinality the spaces and are weakly sequentially homeomorphic.

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