Assuming the validity of the equivalence principle in the quantum regime, we argue that one of the assumptions of the usual definition of quantum mechanics, namely separation between the classical'' detector and the quantum’’ system, must be relaxed. We argue, therefore, that if both the equivalence principle and quantum mechanics continue to survive experimental tests, that this favors epistemic'' interpretations of quantum mechanics (where formalism is built around relations between observables) over ontic ones’’ (assuming the reality of states and wavefunctions). In particular, we show that relational type interpretations can readily accomodate the equivalence principle via a minor modification of the assumptions used to justify the formalism. We qualitatively speculate what a full generally covariant quantum dynamics could look like, and comment on experimental investigations.

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