This article is devoted to developing an approach for manipulating the von Neumann entropy of an open two-qubit system with coherent control and incoherent control inducing time-dependent decoherence rates. The following goals are considered: (a) minimizing or maximizing the final entropy ; (b) steering to a given target value; © steering to a target value and satisfying the pointwise state constraint for a given ; (d) keeping constant at a given time interval. Under the Markovian dynamics determined by a Gorini–Kossakowski–Sudarshan–Lindblad type master equation, which contains coherent and incoherent controls, one- and two-step gradient projection methods and genetic algorithm have been adapted, taking into account the specifics of the objective functionals. The corresponding numerical results are provided and discussed.

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