In quantum thermodynamics, entropy production is usually defined in terms of the quantum relative entropy between two states. We derive a lower bound for the quantum entropy production in terms of the mean and variance of quantum observables, which we will refer to as a thermodynamic uncertainty relation (TUR) for the entropy production. In the absence of coherence between the states, our result reproduces classic TURs in stochastic thermodynamics. For the derivation of the TUR, we introduce a lower bound for a quantum generalization of the divergence between two states and discuss its implications for stochastic and quantum thermodynamics, as well as the limiting case where it reproduces the quantum Cramér-Rao inequality.

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