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We consider a Hele-Shaw model that describes tumor growth subject to nutrient supply. The model is derived by taking the incompressible limit of porous medium type equations, and the boundary instability of this model was recently studied in \cite{feng2022tumor} using asymptotic analysis. In this paper, we further prove the existence of nonsymmetric traveling wave solutions to the model in a two dimensional tube-like domain, which reflect intrinsic boundary instability in tumor growth dynamics.

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