We present a lattice determination of the inclusive decay rate of the process in which the lepton decays into a generic hadronic state with flavour quantum numbers. Our results have been obtained in iso-symmetric QCD with full non-perturbative accuracy, without any OPE approximation and, except for the presently missing long-distance isospin-breaking corrections, include a solid estimate of all sources of theoretical uncertainties. This has been possible by using the Hansen-Lupo-Tantalo method [1] that we have already successfully applied in [2] to compute the inclusive decay rate of the process in the flavour channel. By combining our first-principles theoretical results with the presently-available experimental data we extract the CKM matrix element , the Cabibbo angle, with a % accuracy, dominated by the experimental error.

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