An Overview of the Development of Stereotactic Body Radiation Therapy

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control rate of the tumor and reduce the probability of complications. With the comprehensive development of medical imaging, radiation biology and other disciplines, this less-fractional, high-dose radiotherapy method has been increasingly developed and applied in clinical practice. The background, radio-biological basis, key technologies and main equipment of SBRT are discussed, and its future development direction is prospected.