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In this contribution to the proceedings of the 29th Solvay Conference on Physics I will give an overview of some key challenges in our theoretical understanding of the rheology of glasses, focussing on (i) steady shear flow curves and their relation to the glass and jamming transitions, (ii) ductile versus brittle yielding in shear startup and (iii) yielding under oscillatory shear. I will also briefly discuss connections to the reversible-irreversible and random organization transitions as well as to the broad field of memory formation in materials.

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