We explore the Quantum Chromodynamics (QCD) phase diagram’s complexities, including quark deconfinement transitions, liquid-gas phase changes, and critical points, using the chiral mean-field (CMF) model that is able to capture all these features. We introduce a vector meson renormalization within the CMF framework, enabling precise adjustments of meson masses and coupling strengths related to vector meson interactions. Performing a new fit to the deconfinement potential, we are able to replicate recent lattice QCD results, low energy nuclear physics properties, neutron star observational data, and key phase diagram features as per modern constraints. This approach enhances our understanding of vector mesons’ roles in mediating nuclear interactions and their impact on the equation of state, contributing to a more comprehensive understanding of the QCD phase diagram and its implications for nuclear and astrophysical phenomena.

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