We report on the first quantum Monte Carlo calculations of helium isotopes with fully propagated theoretical uncertainties from the interaction to the many-body observables. To achieve this, we build emulators for solutions to the Faddeev equations for the binding energy and Gamow-Teller matrix element of , as well as for auxiliary-field diffusion Monte Carlo calculations of the charge radius, employing local two- and three-body interactions up to next-to-next-to-leading order in chiral effective field theory. We use these emulators to determine the posterior distributions for all low-energy couplings that appear in the interaction up to this order using Bayesian inference while accounting for theoretical uncertainties. We then build emulators for auxiliary-field diffusion Monte Carlo for helium isotopes and propagate the full posterior distributions to these systems. Our approach serves as a framework for studies of atomic nuclei with consistently treated and correlated theoretical uncertainties.

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