We present observations using the NOrthern Extended Millimetre Array (NOEMA) of CO and emission lines, and the underlying dust continuum in two quasars at , i.e., P215-16 at = 5.78 and J1429+5447 at = 6.18. Notably, among all published CO SLEDs of quasars at , the two systems reveal the highest and the lowest CO level of excitation, respectively. Our radiative transfer modeling of the CO SLED of P215-16 suggests that the molecular gas heated by AGN could be a plausible origin for the high CO excitation. For J1429+5447, we obtain the first well-sampled CO SLED (from transitions from 2-1 to 10-9) of a radio-loud quasar at . Analysis of the CO SLED suggests that a single photo-dissociation region (PDR) component could explain the CO excitation in the radio-loud quasar J1429+5447. This work highlights the utility of the CO SLED in uncovering the ISM properties in these young quasar-starburst systems at the highest redshift. The diversity of the CO SLEDs reveals the complexities in gas conditions and excitation mechanisms at their early evolutionary stage.

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