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2024-01-04
AGuIX nanoparticle-nanobody bioconjugates to target immune checkpoint receptors
Léna CarmèsGuillaume BortFrançois LuxLéa SebanPaul RocchiZeinaf MuradovaAgnès HagègeLaurence Heinrich-BalardFrédéric DelolmeVirginie Gueguen-ChaignonCharles TruilletStephanie CrowleyElisa BelloTristan DoussineauMichael DouganOlivier TillementJonathan SchoenfeldNeeda BrownRoss Berbeco
文献摘要
Comparison of click chemistry and sortagging grafting strategies for functionalizing AGuIX nanoparticles with nanobodies to develop a tri-functional technology combining MRI imaging, radiotherapy, and immunotherapy by inhibiting immune checkpoints.
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