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A nonlinear cross-diffusion–fluid system with chemical terms describing the dynamics of predator-prey living in a Newtonian fluid is proposed in this paper. The existence of a weak solution for the proposed macro-scale system is proved based on the Schauder fixed-point theory, a priori estimates, and compactness arguments. The proposed system is derived from the underlying description delivered by a kinetic-fluid theory model by a multiscale approach. Finally, we discuss the computational results for the proposed macro-scale system in two-dimensional space.

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